The Research Of Preoperative Radiation For Prophylaxis Against Heterotopic Ossification

Objective: Heterotopic ossification (HO) is the mature bone in parenchyma surrounding the arthrosis. Since 1970 total hip arthroplasty and opration of acetabulum fracture were spreaded, more heterotopic ossification occurd. Prophylactic methods aimed at inhibiting heterotopic ossification have included pharmacological measures and radiation therapy. Pharmacological measures (nonsteroidal anti-inflammatory agents) were not accepted widely for inconsistent compliance by patients and side affect. Limited-field radiation prophylaxis enables localization of its inhibitory effect on bone formation while avoiding systemic complications, so it become the trend to prophylaxis HO. Radiation treatment can be applied preoperative and postoperative. For reasons of patient comfort and safety (for example, to avoid prosthetic hip dislocation during transport and positioning of the patient in the radiation suite), it is desirable to administer radiation treatment preoperatively. Reference the study and experience national and international, we compared the efficacy of radiation delivered at four preoperative time points, ranging from four hours to two weeks, for prevention of heterotopic ossification after hip surgery, and determine the optimal preoperative timing of...