The Relationship Between The Serum IGF-1 Level And Type2 Diabetic Retinopathy In Uygur

Objective: To explore the relationship between the occurrence and development of Uygur type2 diabetic retinopathy and the level of serum IGF-1. Methods: To apply the technique of radioimmunoassay to measure the amounts of IGF-1 in serum of 20 normal cases, 20 cases with non-diabetic retinopathy (NDR), 25 cases with background diabetic retinopathy (BDR), and 23 cases with proliferative diabetic retinopathy (PDR). To apply single-factor variance analysis to carry out statistics comparison. Results: The serum IGF-1 level of NDR (139.122±21.144) is higher than normal group (134.553±33.168); the serum IGF-1 level of BDR (159.468±28.961) is higher than NDR (139.122±21.144); the serum IGF-1 level of PDR (179.284±22.096) is higher than BDR (159.468± 28.961); and the serum IGF-1 level of DR (168.973±27.509) is higher than NDR (139.122±21.144), and the serum IGF-1 level is increasing with the lasting of course and the developement of state of illness in diabetic patient. Conclusion: The serum IGF-1 level of patients with Uygur type2 diabetic might involve the occurrence and development of Uygur type2 diabetic retinopathy, which accords with other domestic and international researches in terms of different nations.