| GongYanJing Tablet is derived from clinical compound prescription, and composed of the effective components after activity filtrations, which are extracted and separated from Guangdongzizhu and Yimucao.It has the effects of clearing heat and detoxifcaton, promoting blood circulation and reducing bruise, draining humidity and detumescence.It is maily used in treating various acute and chronic cervicitis.This project mostly aims at testifying the effects of GongYanJing Tablet on prevention and treatment of cervicitis and further evaluateing the mechanism of its effects.1The protective effects of GYJ on experimental cervicitis ratsOBJECTIVE: To study the effects of GongYanJing Tablet on morphological changes. METHODS: Two modified cervicitis models are made according to reports , which respectively are induced by Escherichia coli and phenol gelatinoid.HE staining of cervices is performanced to observe morphological changes, then score the changes according to standard of classification classification. RESULTS: After molding of cervicitis models, in the vehicle group, great number of cervical squamous epithelia appeare growths, edema, even partial area occurr ulceration, denaturalization and putrescence, then desquamate, with leukocyte infiltration in the surface even under layer of cervical mucousa.The status is improved by GongYanJing Tablet. CONCLUSION: GongYanJing Tablet can relieve morphological damage in cervical inflammation.2The anti-inflammatory effects of GYJOBJECTIVE: To observe the anti-inflammatory effects of GongYanJing Tablet. METHODS: Make the rat models of paw-adema induced by Carrageenan and acestoma induced by tampon, then measure the cubages of varicose paws and the weights of acestomas. RESULTS: Both Carrageenan-induced paw-edema and tampon-induced acestoma are significantly inhibitted by GongYanJing Tablet.
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