The Clinical Effect Of Renal Allograft On The Minorities And Hans In Xinjiang

Objective: To analyze various factors concerning graft survival rates of the minority and Han patients receiving cadaveric renal allografts, especially the factor of nationalities. To see the clinical effect of renal allograft between different nationalities so as to provide clinical proof for renal allograft between different nationalities in Xinjiang. Methods: Both retrospective and prospective designs were used. Relevant data were reviewed for 331 patients receiving cadaveric renal allografts, whose gender, age, nationality, the primary affection, the hemodialysis time, the warm and cold ischemia time of the donor kidneys, the degree of tissue match, the times of allograft, the scheme of restraining immunity, the incidences of hyperacute rejection, the incidences of accelerated rejection, the incidences of acute rejection and the incidences of medical and surgical complication were analyzed through the statistical method of unifactor and multifactor. Results: There is no statistical difference between the minority group and the Han group as to the common conditions before transplantation. Though the renal allograft survival rates of the Hans are higher than those of the minorities(1st year 90.28% Vs 83.33%, 3rd year 76.79% Vs 68.92%), there is no statistical difference as to the influence of the nationalities of patients on the renal allograft survival rates. The incidences of acute rejection are very important for the renal allograft survival rates ( P=0.0209) , and it is the only factor chosen in the statistical analysis of multifactor. The scheme of restrainingimmunity can affect the renal allograft survival rates to a certain degree (P=0.0152) . The other factors including gender, age, the primary affection, the hemodialysis time, the warm and cold ischemia time of the donor kidneys, the degree of tissue match, the times of allograft, the incidences of hyperacute rejection, the incidences of accelerated rejection and the incidences of medical and surgical complication have no effect on the renal allograft survival rates. Conclusion: There is no statistical difference between the minority group and the Han group as to the common conditions before transplantation. The clinical effects of the minority and Han patients receiving cadaveric renal allografts are similar. The incidence of acute rejection is an important factor affecting the renal allograft survival. The scheme of restraining immunity can affect the renal allograft survival rates to a certain degree.