Clinical Investigation Of Bacterial Translocation In Patients With Cirrhosis

Abstract: Objective The aim of the study was to investigate the prevalence and associated risk factors for bacterial translocation ( BT ) in patients with cirrhosis, analyzed clinical data to understand significance of BT in liver transplant. Methods Mesenteric lymph nodes portal vein blood peripheral blood were obtained for microbiological culture from 78 patients with cirrhosis, clinical data were analyzed to screening the risk factors for BT and the correlative complications after liver transplant. Results BT was identified in 8 (10.3 percent) of 79 patients. Independent preoperative variables associated with BT was Bilirubinemia (P=0. 022) .BT was independently associated with an increased infection rate after liver transplant (P=0. 05) . Conclusions The prevalence of BT in patients with cirrhosis is 10.3%;Bilirubinemia is the risk factor of BT;BT can increase infection rate after liver transplant.