Analysis Of Measured Results Of OAE In High-risk Neonates

1.Objective: To investigate the effects of hyperbilirubinemia, prematurity and asphyxia on neonatal hearing,and to evaluate the performance of transiently evoked otoacoustic emissions(TEOAEs) and distortion produced otoacoustic emissions (DPOAEs) in high-risk neonatal hearing screening. 2.Methods: The standards of Celesta 503 Cochlear Emission Analyzer proposed by Liao Hua etc.from the Department of Otolaryngology of the First Affiliated Hospital of Hubei Medical College were adopted.Those standards are as follows: 錾the criterion of passing TEOAEs screening was based on the coefficient of waveforms equal to or greater than 0.60 (r≥0.60); 鍪the pass criterion of DPOAEs was set as that the response levels were greater than the preset lower limits of normal range in more than five out of eight frequencies (0.75,1.0,1.5,2.0,3.0,4.0, 6.0,8.0kHz). 87 high-risk newborns and 27 normal newborns in our hospital were screened. The pass-rates of the measurement of TEOAEs and that of DPOAEs in high-risk neonates (the hyperbilirubinemia group, the premature group, the asphyxia group and the compound group) were compared to that of normal neonates. The data was analyzed by SPSS 12.0. ˉx ±s represents means. x2 test was used in the comparison of different groups, and the difference would be considered significant if P<0.05. 3.Results: The pass-rates of the measurement of TEOAEs and that of DPOAEs of 87 high-risk newborns (174 ears) were 64.37%(112/174), 66.67%(116/174) respectively. The pass-rates of TEOAEs of the hyperbilirubinemia group, the premature group, the asphyxia group and the compound group were 69.57%(32/46), 63.33%(19/30), 63.64% (42/66) and 59.63%(19/32). The pass-rates of DPOAEs were 73.91%(34/46), 66.67% (20/30), 63.64%(42/66) and 62.50%(20/32). The pass-rates of TEOAEs and DPOAEs of 27 normal newborns (54 ears) were 90.74%(49/54) and 94.44%(51/54). The pass-rates of TEOAEs and DPOAEs of the hyperbilirubinemia group, the premature group, the asphyxia group and the compound group were lower than normal neonates, there were significant differences in the statistical analysis. There was no difference between TEOAEs and DPOAEs in neonatal hearing screening. 4.Conclusion: 錾The pass-rates of OAE of the hyperbilirubinemia group, the premature group and the asphyxia group were significantly lower than that of normal neonates, which indicates that hyperbilirubinemia, prematurity and asphyxia are all high-risk factors of hearing impairment.High-risk neonates are the high-risk population of hearing lose.Hearing screening for high-risk neonates is of much more significant. 鍪There was no difference between TEOAEs and DPOAEs in neonatal hearing screening.Both TEOAEs and DPOAEs are considered to apply to the primary hearing screening.