| Objective: To determine the clinical efficacy and safety of low dose fentanyl added to ropivacaine in subarachnoid block for cesarean section. Methods: Eighty patients with ASA physical status â… and â…¡ scheduled to undergo cesarean section for delivery were randomly allocated to receiving spinally mixture none fentanyl (group R) , 5μg fentanyl (group F5), 10μg fentanyl(group F10), and 15μg fentanyl(group F15), combined with 1% ropivacaine 1 ml and 10% glucose 1 ml and diluted to 3 ml with normal saline respectively, after combined spinal-epidural anesthesia puncture was applied at the L2 ~ 3 interspace. Heart rate, blood pressure, the sensory and motor block were recorded at regular intervals and compared in all four groups. The adverse effects and neonatal outcome were observed. Result: There was a statistically significant fall in blood pressure in all four groups after subarachnoid block (P<0.05) , but no differences in clinical hypotension were observed. The recovery of sensory block was prolonged significantly in group F10 and group F15 than in group F5 and group R (P<0.05) . There were no differences in adverse effects and neonatal outcome. Conclusions: Ropivacaine with 10 μ g fentanyl is safe and effective in subarachnoid block for cesarean section.
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