Experimental Study Of Long-Segment Tracheal Allografts Undergoing Revascularization

Objective: To study the research way in tracheal allografts undergoing revascularization .Methods: Tracheal transplantation is still in the periodofanimal experiment.The principal factors which prevent tracheal transplantation applied clinically are revascularization of grafts,immunosuppression and long-term preservation of grafts.Omentopexy is an effective method for revascularization of tracheal graft.The tracheal allograft is embedded in the omentum.then the second-stage tracheal transplantation approach with pedicled omentum can increase the rate of successful revascularization, and reduce the rate of infection of grafts.There is a limit to the length of tracheal transplantation with revascularization.To solve the problem, To use tracheal cartilages stand of variant donator , omentum and intestinalmucosa of recipient to make tracheal surrogate ,and this method can extend the length of tracheal transplantation.Results: Compared with the one-stage tracheal allograftapproach using the great eromentum,the two-stage approach could increase the successful rate of revascularization and reepithelialization,and made the allografts accord with their physiology.Conclusion:lf the approach is successful,it can reduce graft-rejection> prevent graft-collapse and increase graft-viability after tracheal allograft.