The Value In Diagnosis Of Meningiomas With DTI

Objective: To investigate the relationship of ADC values, FA values, Fibertracking maps and pathological grade in meningiomas by using DTI. Materialand Methods:27 cases of meningiomas with pathologic confirmation underwentroutine MRI, DWI, DTI and enhanced scaning. ADC and FA values weremeasured in the solid part of tumors, the peritumoral edema, the white mattersurrounding the edema and corresponding normal brain. Bilateral white matterwere 3D reconstructed . Results: â‘  FA values of the solid part of tumors werelower than the values of intact side corresponding normal brain. ADC values ofthe peritumoral edema were higher than the values of corresponding normalbrain. FA values of the white matter surrounding the edema were higher than thevalues of corresponding normal brain. All of the differences were statisticallysignificant.â‘¡ Benign meningiomas: There was significant difference of ADCvalues in the solid part of tumors, the peritumoral edema and the white mattersurrounding the edema. FA values of the white matter surrounding the edemawere higher than the values of the solid part of tumors and the peritumoraledema respectively, and the difference was significant. The result of themalignant meningiomas is same as the result of the benign tumors. â‘¢ Thedifference of ADC values in the solid part of tumors was statistically significantbetween malignant meningiomas and benign tumors. There was significantdifference of FA values in white matter surrounding the edema betweenmalignant meningiomas and benign tumors. â‘£13 of benign meningiomas led toa corresponding large displacement of the fiber away from the tumor. In 6 ofbenign meningiomas, the fiber was not seen to be separate from the tumorobviously. The fiber of malignant meningiomas is not only displaced butinfiltrated by the tumor. Conclusion: ADC and FA values may predict themalignancy of meningiomas. ADC and FA values can be used to differentiatethe solid part of the tumors, the peritumoral edema and the white mattersurrounding the edema. Fiber tracking maps provide the information regardingthe detailed relationship between meningiomas and nearby white matter tracts.Combined with conventional MR imaging, DTI can provide importantinformation in planning brain tumor surgery and prognosis.