Study On The Valve Of Magnifying Chromoendoscopy And Chromoendoscopy In Detection And Diagnosis Of Colorectal Protrude Lesions

Objective: To study the clinical value of magnifying chromoendoscopy and chromoendoscopy in detection and diagnosis of colorectal protrude lesions.Methods: A total of 64 colorectal protrud lesions in 30 patients were included from march 2004 to march 2005.All lesions detected on colonoscopy were first diagnosed using the conventional view. Then 0.4% indigo camine solution was spayed on the lesion mucosa surface at chromoendoscopy and finally at magnifying chromoendoscopy. The diagnosis at each step were recorded consecutively .All lesions were finally polypectomy or biopsy for histological diagnos . All examinations were performed by a single endoscopist.Result : The diagnostic accuracy of conventional colonoscopy, chromoendoscopy and magnifying chromoendoscopy compared with histological diagnosis of inflammatory polyps,tubular adenomas,villous adenomas and colorectal cancer was 68.8%, 76.9%, 66.7% and 80% respectively and 86.7%, 87.5%, 85.7% and 90.9% respectively and 93.3%, 91.7%, 92.9% and 90.9% respectively.the overall diagnostic accuracy of three procedures was 73.4%,87.5% and 92.2% respectively. Conclusions : Magnifying chromoendoscopy with indigo carmine dye is the most reliable and a useful method for differentiating neoplastic from non-neoplastic lesions of the colorectum .Chromoendoscopy could be used as a routine procedure in order to enhance the early diagnosis of colorectal cancers. however, this technique is not a substitute for histology in current state .