Correlative Research Between Male Osteoporosis And Endothelin

Objectives : The aim of study was to explore the relationship of Male Osteoporosis and Endothelin , To provide the foundation on the pathological mechanism of male osteoporosis and it's syndrome types as well as illustrate the essence of differentiation of syndromes at microcosmic level.Method : 39 cases of male patients from Affiliated Orthopedics Hospital of Guangzhou University of Traditional Chinese Medicine were measured serum level of Estrogen(E2), Testosterone(T) EndotheIin(ET),and bone mineral density ,and diagnosis their TCM syndromes type according to the principle of the differentiation of syndromes,SPSS 11.5 software was applied to analyze their correlations and distinct differencesResults : (1)the result of correlative analysis between the age and serum level of T,the correlation coefficient r=-0.096, the scatter diagram showed that the serum level of T had tendency of decreasing along with the increasing of the age,which indicated negative correlation between them;(2) the result of correlative analysis between the age and E2, P< 0.05, the correlation coefficient r=0.374, the scatter diagram showed that the curve of E2 had marked tendency of increasing along with the increasing of the age,which indicated significant positive correlation between them;(3) the result of correlative analysis between theT and E2, P<0.05, the correlation coefficient r=0.388, the scatter diagram showed that the curve of T had marked tendency of increasing along with the increasing of the E2,which indicated significant positive correlation between them; (4)the result of correlative analysis between the age and serum level of ET,the correlation coefficient r= 0.718, indicated negative correlation between age and serum level of ET. The scatter diagram showed serum level of ET keep on certain level with the increasing of age.(5)the result of correlative analysis between the level of ET and serum level of T,the correlation coefficient r= -0.013 indicated negative correlation between the level of ET and serum level of T; the scatter diagram showed that the serum level of ET keep on certain level and correlation had no significance between serum level of ET and T. (6) the result of correlative analysis between the ET and E2, the correlation coefficient r= 0.035. indicated positive correlation between ET and E2. the scatter diagram showed that both of them kept certain level and had no significant difference. (7) The comparison of the mean serum level of E₂ among four...