| Objective:Tei index is a new index which was put forward in recent years for analysis of global cardiac dysfunction. It is defined as the sum of isovolumic contraction time (ICT) and isovolumic relaxation time (IRT) divided by ejection time (ET).It comes from IRT, ICT and ET which is used to appraise cardiac function. Tei index not only combines these time intervals,but also it is simpler in measuring and calculating than IRT, ICT and ET.The systolic function and diastolic function of cardiac muscle often are damaged at the same time. Thus Tei index is more scienficable and reasonable in reflecting cardiac dysfunction than other isolated systolic or diastolic function index . This study was to probe into clinical value and affecting factors of Tei index in assessing right ventricular (RV) function. Methods: The study population comprised 26 patients with left asymmetrical ventricular hypertrophic cardiomyopath (HCM), 20 patients with dilated cardiomyopathy (DCM), 15 patients with pulmonary hypertension by pulmonary disease (PH), 20 patients with atrial septal defect (ASD), 26 patients with pulmonary hypertension by ASD, 12 patients with tricuspid regurgitation and 47 age-and sex-matched contral subjects.The interval b is ejection time which is measured from the right ventricular outflow Doppler signal. The interval a is the sum of right ventricular isovolumetric contraction time and isovolumetric relaxation time which is obtained by subtracting right ventricular ejection time from the interval between cessation and onset of the tricuspid inflow measured from the tricuspid inflow velocity profile with pulsed-wave Doppler echocardiography. The Tei index is defined as the sum of the isovolumetric contraction (ICT) and isovolumetric relaxation intervals (IRT) divided by the right ventricular ejection time (ET). Tei index is calculated as (a-b)/b. At the same time ,linking the electricardiography. Other available intervals include isovolumetric relaxation time measured (c-d) by subtracting interval (d) between R wave and cessation of right ventricular outflow from interval (c) between R wave and onset of tricuspid flow. Isovolumetric contraction time obtain by subtracting IRT from (a-b).From IRT,ICT,ICT/ET,IRT/ET, we can know the systolic and diastolic function of right ventricular respectively. Measuring all subjects' heart rhythm (HR ), right ventricular end-diastolic dimension, and systolic pulmonary artery pressure in PH patients.We compared patient groups and normal group in HR,IRT,ICT,ET,ICT/ET,IRT/ET,Tei index to know if there was statistical difference,and master the right ventricular function.we also objected the correlation with RV Tei index and HR,age and right ventricular end-diastolic dimension to summarize and judge the influencefactor that Tei index appraises the right ventricular function. Result: ①Compared with the patient groups and normal control groups, the patients with HCM ,there was not statistical difference in their HR, IRT and ICT were prolonged (60.24±31.55 vs 33.19±22.76 , p=0.0009 ; 47.20±17.80 vs 36.18±19.69,p=0.0415), there was not statistical difference in ET, IRT/ET and ICT/ET were elevated (0.21±0.11 vs 0.11±0.07, p=0.0005; 0.16±0.07 vs 0.12±0.06, p=0.0131),Tei index was significantly increased(0.37±0.13 vs 0.22±0.07,p=0.0001);the patients with DCM , their HR was significantly increased (93.60±16.25 vs 69.30±12.96,p= 0.0000), IRT, ICT, IRT / ET and ICT / ET were significantly increased, (126.27±41.79 vs 35.24±22.04,p=0.0001; 92.34±40.20 vs 35.37±22.52,p=0.0001; 0.66±0.28 vs 0.11±0.07, p=0.0001; 0.48±0.26 vs 0.11±0.07, p=0.0001) , ET was significantly shorten (198.25±36.23 vs 319.75±31.14,p=0.0000),Tei index was significantly increased ( 1.13±0.38 vs 0.22±0.06 ,p=0.0001 ); the patients with pulmonary hypertension by pulmonary disease, their HR was significantly increased (89.00±12.94 vs 66.73±11.00,p=0.0000),IRT, ICT, IRT/ET and ICT/ET were significantly increased (143.11±56.12 vs 43.47±25.80,p=0.0001; 84.69±36.15 vs 41.09±22.64,p= 0.0006; 0.58±0.16 v...
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