| Objective:This study was designed to investigate the influence of implant autograft bone in cleft palate on maxillary growth in rats.Methods:Forty Wistar strain male rats aged 4 weeks were randomly divided into four groups.Each group had 10 rats.The first group was the unoperated control group.The second group had a surgically created cleft palate but unrepaired .The third group also had a surgically created cleft palate which followed by a two-flap palatoplasty repair immediately.The experiment group also had a surgically created cleft palate ,but the cleft palate was reconstructed by implanting a piece of autograft rib bone with two-flap repair.All animals were sacrificed on the 10th week after operation.Metricranial variables were measured from the clean skulls and lateral cephalometric films.Results: The experiment group was significantly smaller than unoperated control group and cleft palate group in the maxillary widths,length(AD),development variables (E-Bu,Mu-Bu,Mu-Pr), height variables(U1-PoE,U3-PoE,Iu-PoE) and variables of occlusal plane(U1U3/SoE) (P﹤0.05).Except that the experiment group had significantly greater posterior palate width than two-flap repair group(P﹤0.05),there were no significantly difference between the two procedures in maxillary growth variables(P﹥0.05).But the experiment group was smaller in the maxillary heights,length variables mean than the two-flap group. The two-flap group had significantly difference in maxillary widths and the variables of occlusal plane(U1U3/SoE) with the cleft palate group(P﹤0.05). Except the maxillary widths,most of variables between the unoperated control group and cleft palate group had no significantly difference(P﹥0.05). Conclusions:These fingings showed that both the two palatoplasty had inhibited the maxillary three-dimensional development. The cleft palate was repaired by implanting autograft rib bone had positive effect on preventing the constraction of palate width.But in the maxillary anteroposterior and vertical development, the experiment group possibly had more severe retardation than two-flap repair group. |
