Study On Natural Produce Of Flavonoids Extraction Methods And Its Comparison

Flavone drugs have the effects of anti-cerebra ischemia, anti-myocardial ischemia, anti-cardiac amhyth, analgesic, protecting liver, protecting alimentary ulcer, anti-virus, anti-cancer, and so on. Otherwise, many researches indicate that flavone natural drugs have the pharmacologicals of blood Pressure depressing, lowering blood lipide, inhibiting platelet aggregation. So it was taken into account by governments, pharmaceutical and food industries, and the researches of flavone natural produce in food. The extraction of flavone natural produce was the key point of its research and development, the most effective extractive and design method was used to the flavone of pueraria and hawthorn after all kinds of extraction means were thoroughly analyzed, and the analysis comparative evaluating system of flavone natural produce was established.As for the extraction of pueraria flavones, the best extractive result was supersonic wave method. And the best extractive craft were: 75min of supersonic time, 100w supersonic power, 150 mesh, 40% alcohol, 20:1 liquid and solid ratio, the actual extractive rate was 2.21%, and the relative extractive rate was 85.33%. As for the extraction of hawthron flavones, the best extractive result was microwave method. And the best extractive craft were 25min of microwave time, 117w microwave power, 45% alcohol, 20:1 liquid and solid ratio, under these conditions, the actual extractive rate is 8.23%, and the relative extractive rate is 83.81%.Even-design method could easily get the best extractive craft conditions of the experiment, it could be commended to improve work efficiency in the field of natural produce extraction. It has the following characters:The regression model of supersonic wave extracting pueraria flavones was: Y=1.885-0.370X4-0.00233X3+0.0186X5+ 0.0327X12+0.0927X42-0.0202X1*X4+0.00337X1*X5-0.00457X2*X4; The regression model of micro wave extracting pueraria flavones was:Y=0.627-0.0268X1*X3+ 0.00756X2*X4+0.0613X3*X4; The regression model of supersonic wave extracting hawthron rutin was: Y=-10.335+3.124X4+7.94X5-0.367X42-0.741X52+0.0260X1*X4-0.0451X2*X3+0.146X2*X5-0.667X4*X5; The regression model of micro wave extracting hawthron rutin was: Y=4.200+0.527X2-0.211X1*X2+0.0749X2*X3-0.0898X2*X4; The regression model of SBE extracting hawthron rutin was: Y=-0.809-0.0223X3+ 0.000818X72+0.00356X1X4+0.000440X2X4-0.00893X3X4+0.0153X3X5+0.000100X3X6+0.00473X4X5+0.0000794X5X6.The analysis comparative model which was based on fuzzy mathematics and the analytic hierarchy process (AHP) was very effective. The model not only fundamentally reflected the efficiency of adopting craft mend method, but also semi-quantitly reflected the effect of extractive method, craft and efficiency, but the precise degree is still needed to further research and mend; At the same time, this model can estimate the best extractive craft conditions by analyzing the related references before extraction. In order to predict the extraction, the results can be calculated through the model, and the general tendency of model was according with actual extraction.