The Prevalence Survey For Peripheral Arterial Occlusive Disease(PAOD) In Elderly People With Lipoprotein Abnormalities

Objection: To analyses the prevalence of Peripheral Arterial Occlusive Disease in elderly people with lipoprotein abnormalities, and provide the theoretical support to clinical study.Subjects and Methods: A cross-sectional survey for PAOD, 2124 subjects from 9 residential communities were randomly selected out of 20411 elderly people within 94 residential communities on Wan- shou-lu area, Peking. There were 943 men, and 1181 women. The age varied 60-95 years, mean 68.54±5.43(mean± SD) years.PAOD was defined by a noninvasive testing, as an abnormal ankle-arm index (AAI). PAOD was considered present if the AAI was 0.90 or less. According to the National Cholesterol Education Project (NCEP) and Adult Treatment Project Ⅲ (ATP Ⅲ), the criterion of lipoprotein abnormalities was any one of the following four items: Triglycerides (TG) ≥2.26 mmol / L, or/and Total Cholesterol (TC) ≥5.72 mmol/L,or/and Low-Density Lipoprotein (LDL) ≥3.64 mmol / L, or/and High-Density Lipoprotein (HDL) ≤1.04 mmol / L. Results:There were 1071 (male 410, female 661) people suffered from lipoprotein abnormalities, aged 68.3 ± 5.40 (mean ± SD) years (60-92 years old), and the prevalence of lipoprotein abnormalities was 50.42 %. Among them the people with PAOD were 184 (male 60, female 124), the prevalence of PAOD was 17.18%. The prevalence of PAOD in various lipoprotein abnormalities respectively is: 14.12% in hypertriglyceridemia; 10.10% in high low-density lipoprotein levels; 15.94% in hypercholesterolaemia; 19.65% in lower high-density lipoprotein levels; 19.18% in lipoprotein abnormalities merged with hypertension. The prevalence of PAOD in patients with hypertension was 14.98%, 19.476% in lipoprotein abnormalities merged with the diabetic, 15.38% in Diabetic, 42.86% in advanced elderly patients with lipoprotein abnormalities, etc. Conclusions: Lower high-density-lipoprotein levels is an independent risk factor for PAOD; The prevalence of PAOD was no significant difference in different lipoprotein abnormalities. Lipoprotein abnormalities merged other risk factors will increase the prevalence of PAOD. The prevalence of PAOD in advanced elder with lipoprotein abnormalities is 2-3 times than in common elder. In conclusion, we should actively treat the elder with lipoprotein abnormalities. Especially, we should prevent and control the risk factors of PAOD, such as advanced elder, lipoprotein abnormalities and elders merged with other risk factors.