Prognostic Value Of Cardiac Troponin I And C-reactive Protein Levels After Percutaneous Coronary Intervention In Non-ST Elevation Acute Coronary Syndrome

Objective To investigate the prognostic value of cardiac troponin I (cTnI) and C-reactive protein (CRP) levels after percutaneous coronary intervention (PCI) in non-ST elevation acute coronary syndrome (ACS). Methods cTnI and CRP levels were measured after PCI in consecutive patients with non-ST elevation myocardial infarction (NSTEMI) or unstable angina (UA). The cases were divided into groups according to the cTnI and CRP levels after PCI. The major adverse cardiovascular events (MACE) were analyzed. Results The incidences of non-fatal myocardial infarction, cardiac death and total MACE significantly increased in cTnI elevated group than that in cTnI normal group (all P<0.05). The incidences of total MACE in CRP elevated group is higher than that in CRP normal group (P<0.05). The incidences of total MACE significantly increased in group B (cTnI≥0.4μg/L or CRP≥3mg/L) and group C (cTnI≥0.4μg/L and CRP≥3mg/L) than that in group A (cTnI<0.4μg/L and CRP<3mg/L) (all P<0.01). The incidences of total MACE in group C is higher than that in group B (P<0.05). Conclusion cTnI and CRP levels after PCI were associated with the overall incidences of MACE in non-ST elevation acute coronary syndrome. They could be used as markers for risk stratification in non-ST elevation acute coronary syndrome. cTnI and CRP combined together is more valuable than one of them in prognosis.