The Study On The Distribution Of Lung Cancer Associated Antigen Detected By Monoclonal Antibody N-35 In Serum.

Purpose.To study the difference and the significance of the distribution of lung cancer associated antigen in sera.Methods:By Western Blot method examining lung cancer associated antigen detected by monoclonal antibody N-35 in sera of fifity cases with malignant tumor , seventy-two cases who are healthy with two or three positive lung tumor markers, ninety-six cases who are healthy without positive lung tumor markers respectively.Results:The positve rate is 42%,2.77%,0% in the MTG,HGWLTM,HGNLTM respectively,There is statistical significance between MTG and HGWLTM,between MTG and HGNLTM(p < 0.01),not statistical significance between HGWLTM and HGNLTM(p > 0.05),the positive rate of lung cancer group is higher than the other malignant tumor group,but there is no statistical significane(p > 0.05) Conclusion:Lung cancer associated antigen detected by monoclonal antibody N-35 significantly exists in sera of malignant tumor cases,specially lung cancer cases,less exists in sera of health cases.