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The Change And Predictive Value Of Pulmonary Function Of Sleep Apnea Syndrome In Children

Posted on:2005-11-17Degree:MasterType:Thesis
Country:ChinaCandidate:X Y ChenFull Text:PDF
GTID:2144360125452508Subject:Academy of Pediatrics
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It is well known that sleep apnea syndrome of children is a substantial dangerous disease. The history of sleep disorder may influence not only growth health and aspects of a child's life, but also affect health issues. In addition to clinical parameters, polysomnography (PSG) is recognized as the gold standard for diagnosis of SAS, but is both expensive and time-consuming, and require resources and facilities that are not widely available, thus simpler, more available and less expensive alternatives to PSG for SAS are studied during the past twenty years.Overnight PSG was conducted on 36 snorers with suspected SAS. defined PSG(+) as an apnea-hypopnea index(AHT)>=5 and LSaO2<90%, SaO2>%. All patients with snoring and sleep apnea were evaluated pulmonary function used impulse Oscillation technique (IOS). Comparison of the two groups according to the AHI was done using multiple regression and logistic regression analysis.Results: In the 36 cases with suspected SAS, 23 were found to have SAHS. R5 and FEV1/PEF were significantly different in two groups. (p<0.05). R5 is 125.58 ?19.88 and FEV,/PEF is 1.15 ?020(groupl),showed significant increase . the other pulmonary function parameters were not significant differentR and FEVj/PEF were used to develop a model for predicting the probability (p) of having of PSG positive for SAHS. Logit (p)=-12.03446-0.535244 x R5+5.792626xFEVi/PEF. Identical conclusions can be draw from regression analysis between AHI and PEF\ FEF50, r= -0.589, = -0.533. Compared pulmonary function test (PFI) with PSG Sensitivity is 78.26%, specificity is 53.85%. The model help to identify patients with a SAHS risk that is so low as to make PSG unnecessary. Based on our study, there would have obviated the need for PSG in 31 % of our patients.
Keywords/Search Tags:Sleep apnea hypopnea syndrome., Pulmonary-function test, Polysomnography, Respire-resistance
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