Treating Elderly Hypertensive Disease By Getting Rid Of Excess Syndrome

This thesis bring forward the thought of treating elderly hypertensive disease (EH) by getting rid of excess syndrome, and observe the therapeutic effect of HuangLian QingJiang (HLQJ) Mixture in treating elderly hypertensive patients with evil heat and extravasated blood.Because the change of modern environment and life style, for example environmental pollution , fatting eat, contained feeling, lacking exercise, eating good food blindly, the physique of old people changes greatly. Weakness syndrome drops off, and excess syndrome increasingly stands out, which leads to more EH patients with excess syndrome. Excess of evil heat in the interior and extravasated blood in vessel are the mainly mechanism of this disease , and cleaning the heat and detoxifying and invigorating the circulation of blood are the important therapies to it. So we create HLQJ Mixture to treat it, which has the function of cleaning the heat and invigorating the circulation of blood.In clinic, 68 EH patients of 1 or 2 stage with evil heat and extravasated blood are randomly classified into two groups, in trail group patients are treated by HLQJ Mixture and in control group patients are treated by NiuHuang JiangYa pills, one-month was a course of treatment. After treatment the blood pressure of trail group drops more greatly than control group. Ambulatory blood pressure monitoring (ABPM) of trail group is improved obviously. The trail group is superior to control group in improving clinicalsymptom , the lipoprotein in the blood , the hemorheology, the myocardial ischemia. And. the levels of ET, TNF- α and LPO are reduced too. In one word , HLQJ Mixture can not only reduce blood pressure , but also improve clinical symptom and experimental targets. This validates the correctness of treating EH by getting rid of excess syndrome.This study bring forward the completely new thought of treating EH by getting rid of excess syndrome, open up a new way of TCM in EH treating.