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Study On The Effect Of Enzymology,Behavioral Science And The Experession Of β-App Of Alzheimer's Disease Rats With Dihuang Yinzi

Posted on:2005-07-29Degree:MasterType:Thesis
Country:ChinaCandidate:L LiuFull Text:PDF
GTID:2144360122998178Subject:Basic Theory of TCM
Abstract/Summary:PDF Full Text Request
Alzheimer's disease is one kind of degenereratly neuropathic disease, which has the characters of clinical and pathological. Because of the ever-aging population and lack of the effective diagnostic and therapeutic methods, more and more AD patients appeared. Up to now, the pathogenesis of AD hasn't been discovered completely, and there aren't effective medicines to be sure on treating AD generally. In view of the pathogenesis of cerebral ischemia and the clinical experience of professor XieNing, we conduct experimental research about the preventive effect of Dihuang Yinzi to the senile dementia rat, in order to probe into its' therapeutics mechanism.This experiment take rats of which IBO was injected into Meynert as the model animals, and take hydergine group as an opposite group, then we carry out an comprehensive research on the Dihuang Yinzi group concerning the behavioral science, the pathological and biochemical change of NO and NOS. The result proved the effects of Dihuang Yinzi: 1 .It could improve the behavioral function of the AD rats. 2.It could decrease the brain NO and NOS levels. 3.It could improve the pathological change in the AD rats' brain. This research concludes that the Dihuang Yinzi is an effective medicine which can prevent the AD.
Keywords/Search Tags:Alzheimer's disease, Dihuang Yinzi, NO, NOS, IBO, Behavioral science
PDF Full Text Request
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