Clinicals And Diffusion Weighted Imagining In Acute Lacunar Cerebral Infarction Patient

Objective To probe into the clinical value of diffusion weighted imaging(DWI) in diagnosing the early lacunar cerebral infarction.Methods The clinical data of 60 patients with early lacunar infarction(LI) were analyzed and the patients underwent routine magnetic resonance imaging (MRI) sequence and DWI sequence. Readings were performed jointly by four well-experienced neuroradiologists who were unknowing with the cases. The neuroanatomically relevant lesions were identified. All images within one layer were compared, special emphasis placed on the signal intensity and lesion size. All the statistics were analyzed statistically.Results Among the 60 patients, there were 45patients with hypertension(75%), 21 with hyper lipidemia (35%) and 18 with diabetes (30%); The common clinical types are 20 cases of pure motor hemiparesis (PMH) and aberrant types of PMH, 12 cases of lacunar state (LS), 10 cases of asymptomatic lacunar infarction (ALI) and 8 cases of sensorimotor stroke (SMS). The lesion areas could be divided into caudate nucleus (29. 1%), lenticular nucleus (23.3%), corona radiata (15. 1%), thalamus (10. 5%) and internal capsule (7.0%). As for the 20 cases of hyperacute stage (^6h), DWI found the lesion areas while regular MRI did not. As for the 22 cases of acute stage (7~24h), DWI found all the lesion areas and the rate of detection was 100% while MRI found only 12 cases with the rate of 55% (p<0. 05). During the hyperacute and acute period, DWI could show the lesion areas while T2-weighted imaging (T2-WI) couldn' t do and the scope of images increased as time prolonged. DWI could show the lesions more clearly and wholly than T2-WI.Conclusion Hypertension was the direct cause of LI. The lesion areas of LI lay mainly in basal nuclei. Rates of detection were tending upwards in LSand ALI cases and DWI was superior to MRI in diagnosing the early LI cases. DWI should be the prior method of checking early LI.