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Therapy Epilepsy Caused Brain Tumor With Using Multiple Subpial Transection

Posted on:2004-06-10Degree:MasterType:Thesis
Country:ChinaCandidate:H GaoFull Text:PDF
GTID:2144360092998564Subject:Surgery
Abstract/Summary:PDF Full Text Request
Epilepsy is the usual clinical manifestation, also is the eariest and the only manifestation. When the cases whose feature epilepsy with headache and analyze are older than 20s years, especial older than 30s years, we should think the chance of brain tumors. The rate of brain tumor featured by epilepsy is different in statistics, from 20%~80%. Penfield reported that the average rate is 33% in groups. The brain tumor featured by epilepsy ismost in 20s-60s groups, and the rate is decrease after 60s yearsold. To different kind of tumors, the rates are different.Through analysis 323 meningiomas cases from 10~79 years old, Chow reported that the rate is 30% before operation, however the rate is 32.7 post operation.Objective To analyse the histopathology and the factors influencing the outcome of surgical treatment of primary intracerebral neoplasms only prensenting with epilepsy. Methods 43 patients with primary intracerebral tumors presenting with epilepsy without other neurologic signs were retrospectively reviewed. Result 25(58.1%) cases were histologically diagnosedas gliomas among which 19(44.2%) were low-grade and 6(13.9%) high-grade. The incidence of complications for tumor removals was 32.7%. Of the 41patients who had postoperativefollow-up more than 6 months after operation, 18(41.9%) were seizure-free,3 were rare,4 were improved, and 14(34.1%) had no appreciable reductionin seizure frequency. The position of the tumors was significantly correlated with the incidence of postoperative complications and the post operative seizure control (P<0.05).The incidence of postoperative complications for frontal and parietal tumors was higher than that for temporal tumors, while the temporal tumors had better postoperative seizure control than the frontal and the parietal ones.Surgical methods are effect. Especially to para-epilepsy, the seizure can disappear or distinct decrease using the technique of transecting the epileptic focus to 60-80% cases. To the functional focus, we use the Multiple Subpial Transection and Cortex Thermocoagulation so that we can attain good control the seizure besides save the cortex function. We think they are good future. Their main mechanisms are that cutting the transverse fibers in the focus cortex can prevent the horizontal synchronization and spread of epileptic discharge so the main function is normal because of save the length fibers.Conclusions Most of the primary intracerebral tumors only presenting with epilepsy were low-grade gliomas. The position of tumors was an important factor influencing the extent of surgicalremoval and the postoperative seizure control.The article is detail in the operation mechanism and methods and analyses the effect. We think the essential are the accuracy orientation before operation and have utter Multiple Subpial Transect ton and Cortex Thermocoagulation to the focus cortex. We think that Multiple Subpial Transection and Cortex Thermocoagulation can replace the focus transect and save more funtion.
Keywords/Search Tags:intracerebralneoplasm, epilepsy, Multiple Subpial Transection (the MST), Cortex Thermocoagulation
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