The Isovolumic Model On Skeletal Muscle Contractions And Its Electrophysiological Experiments

On the basis of myofibril sliding theory, the isovolumic rodel on skeletal muscle contraction was developed in this paper by modifying the .Huxley model. Meanwhile, the elecUophy-siological experiments on the rabbit gastrocnemius were carried out. The following works about muscular contraction had been done in the paper:1. According to the axisymmetric microstructure of myofibrils and the uncompressibility of the interstitial fluid, the crossbridge kinetic model on muscle contraction proposed by A.F.Huxley was modified on the assumption of isovolume.2. Based upon the present apparatus, the experimental project for the neuromuscular electrophysiology was discussed, which selected rabbit gastrocnemius for its feasibility. Moreover, an experimental platform for fixing preparations was designed and manufactured.3. 16 rabbit gastrocnemius specimens of 8 cases were experimented.4.Experiments on single stimulus and on repetitive stimulus in various frequency to its motor nerve were performed by ueypoint Lite portable electromyography which appliedelectrical pulses and excited the tibial nerve and by Instron 5544 machine which measured isometric tensions. CMAP(complex muscle action potential) also had been recorded by ring surface electrodes.5.By the analysis of the experimental data, the isometric tension as well as the CMAP amplitude and EMG(electromyogram) area increased with the stimulus intensity in a quasi-parabolic relation, while the EMG area varied linearly with the tension generated by muscle contraction. Some valuable conclusions on the EMG were?obtained for the clinical electromyography and exercise instruction.