Evaluation Of The (13)～ C-urea Breath Test In Detecting Helicobacter Pylori Infection

[Objective] To explore the difference and clinic value of the three different detective methods for Helicobacter pylori infection. [Methods] A series of 62 gastric and duodenal disease patients were studied. Detecting HP infection with gastric mucosa pathobiology slice Giensa staining 13C-urea breath test and rapid urease test at the same time. Comparison of 13C-UBT\ RUT and Giemsa staining HP positive rate.[Results] The positive rate of 40 chronic gastritis patients by three different methods are Giemsa staining 67.5%> 13C-UBT 60% and RUT 60%; The positive rate of 22 peptic ulcer patients by different test are Giemsa staining 81.8%, 13C-UBT 72.7% and RUT 68.1%. There was no statistically significant difference between the three methods. The correct rates for diagnosing HP infection of I3C-UBT and RUT were 90.3% and 90.3%. The Sensitivities were 94.7% and 92.3%, the specificities were 83.3% and 87.0%. The positive predictive values were 90% and 92.3%. The negative predictive values were 90.9% and 87.0%. There was no statistically difference between the two tests in the correct rate, the sensitivity, the specificity, the positive predictive value and the negative predictive value.[Conclusion] 13C -UBT appears to be a high accurate, high specific, high sensitive, no radioactive and noninvasive test for diagnosis of HP infection.