The Diagnostic Value Of Detecting TNF-αand IL-6 Concentrations In Serum And Pleural Effusion In Tuberculous And Malignant Pleural Effusion

The diagnostic value of detecting tumor necrosis factor (TNF)-alpha and interleukin-6 concentrations in serum and pleural effusion in tuberculous and malignant pleural effusion Abstract To evaluate tumor necrosis factor 梐lpha(TNF- a ) and interleukin-6(IL-6) in differentiating diagnosis of tuberculous and non-small cell lung cancer with cytology-positive pleural effusion, we measured TNF- a and IL-6 in serum and pleural effusion in 25 patients with tuberculous effusion 21 patients with lung adenocarcinoma~ 11 lung squamous cell carcinoma with pleural effusion and controls by enzyme-linked immunosorbant assays. Serum TNF- a levels in tuberculous pleural effusion patients were lower than that in patients with lung adenocarcinoma and lung squamous cell carcinoma (p