Vertebroplast——Study On The Disposed Ratio Of Domestic Bone Cement And Improvement The Syringe In Experimental And Clinical Application

Purpose: To study the best ratio of bone cement mixed and improve the syringe and seek out the role of injecting bone cement in the process of the percutaneous vertebroplastyMaterials and methods : (1 Bone cement were disposed in different powder-to-monomer ratios with domestic PMMA. The concretionary phases of cement were observed according to both the stages and holding time. Then select one of the most ideal ratio of the mixed cement and ten cement columns were made with it as a trial group. The other ten columns recommended by the literatures were severed as contrast one. These specimens were measured about the biological mechanics in loading and the data of the results were compared. (2)The syringes were improved not only in order to be endured great injection press but to be convenient for injecting cement in procedure. It included laying out the draft of the syringe and manufactured by the related factories. The syringes were adjusted again according to the using status. (3)Twenty adjacent thoracic and lumbar bodies were removed intact from five human corpses. These bodies were divided into two groups, one group were injected by PMMA, the other is severed as contrast. Then twenty vertebral bodies were measured the biological mechanics and the treatment role was evaluated. (4)Twelve healthy dogs were used to trial on PV in lumbar to observe the difficulty extent of injecting this bone cement, and CT was used to evaluate both the diffusions of PMMA and the complications. To decide whether this type syringe are good for injecting bone cement.Results: The most ideal powder-to-monomer ratio is 4 '. 2.6 '0.05). By injecting this kind cement, the loading of these vertebral bodies were increased remarkably (P<0.01). The results of bone cement dispersion in the dog lumbar bodies were significant differences with the two ratiosmixed cement(P<0.05).Conclusion: The ideal bone cement powder-to-monomer ratio is 4 2.6 l[powder(g monomer(ml contrast(ml)]. This type cement and the improved syringe provide the theoretical foundations in developing PV in clinical application.