In order to study the mechanism that chronic myeloid leukemia (CML) was treated with Manbailing capsule, we observed the therapeutic effects of Manbailing capsule in therapy of 20 patients with CML and varieties of soluble interleukin-2 receptor (sIL-2R)~ interleukin-2 (IL-2) of serum, with indirubin as the control group. we conculude that:l.There is no significant difference between the therapeutic effects of Manbailing capsule treating CML(70.0O%) and effects of indirubin (72.22%) (P>O.05), but Manbailig capsule has little significant side reaction or toxic reaction.2.Before treatment,sIL-2R of serum in CML patients were higher than those of health control group significantly (P |