QTL Mapping Analysis Of Economic Traits Of 11 Chromosomes In Liaoning New Breed Of Cashmere Goats

Liaoning new breed of cashmere goats have a significant economic benefit because of the high yield of cashmere and good cashmere fineness, so we pay special attention to improve the fineness and weight of cashmere goat. The constructing of Liaoning new breed of cashmere goat genetic maps and accurate positioning of economic traits QTL could provide accurate and reliable genetic information for breeding, establishment of the core group and further development and use of this breed.A referencing flock having 5 paternal half-sib families totaling 220 individuals from Liaoning new breed of cashmere goat was utilised to construct the genetic maps of 9th, 10th , 11th , 12th , 13th , 14th , 15th , 16th , 18th , 19th and 20th chromosomes in Liaoning new breed of cashmere goats, and made the QTL mapping analysis for 3 economic traits (weight, cashmere yield and fineness).Analyzed the 53 microsatellite loci using popgene software and their population genetics characteristic in Liaoning new breed of cashmere goat, detected the alleles which had an average of 9 alleles (4-13). The average PIC was 0.6901 (0.4617-0.7986) and the average H was 0.9297 (0.7583-1.0000). Those microsatellite loci had 46 high polymorphic and 1 middle polymorphic except 6 single state, which provided a reliable basis for this resources family on the molecular level.The genetic maps of 9th, 10th , 11th , 12th , 13th , 14th , 15th , 16th , 18th , 19th and 20th chromosomes in Liaoning new breed of cashmere goats had an average of 24.6cM spacing between markers, and the order of microsatellite markers were consistent with the sheep genetic linkage map of Versoin 4.3 announced in Australia and USDA-MARC, and SM 4.2 announced in the U.K. Roslin Institute but a little shorter.The QTL analysis of cashmere goat weight, cashmere yield and fineness was performed by using QTL Express. It showed that: on the 9th chromosome, there was a QTL effecting weight in 28 cM between BM2504 and TGLA073; on the 10th chromosome, there was a QTL effecting cashmere yield in 28 cM between McM185 and TGLA272; on 13th chromosome, there was a QTL effecting fineness in 8 cM between BMC1222 to ILZRA; on 20th chromosome, there was a QTL effecting fineness and weight in 32 cM between NPR3 to BMS1719. There were 3 QTL position effecting 3 economic traits between BM2504 and TGLA073, McM185 and TGLA272, BMC1222 to ILZRA and NPR3 to BMS1719.