Study On Response Of Immune Stress Of Chickens For Different Vaccines And Approach Of Inoculation

800 two-week-old chickens were randomly divided into treatment (T) group and control(C). there were 8 repetitions in each group with 20 chicken. The treatment(T) groups were divided into four groups,T1,T2,T3,T4. The C group were injected with normal saline,and T1 group chickens were vaccinated bursa of Infectious Bursal Disease Mild Vaccine, Living(A80 Strain)by putting drop in noses. T2 group chickens were vaccinated with Avian Newcastle Disease Vaccine, Inactivated by putting drop in eyes. T3 group chickens were vaccinated with Avian Newcastle Disease Vaccine, Inactivated by putting drop in noses. T4 group chickens were vaccinated with Avian Newcastle Disease Vaccine, Inactivated by intramuscular injection. After l,3,5,10,15,21 day of inoculation. serum,immune organs,were collected to detect all index defined with 8chicken selected randomly, and killed two bird each time within repetition. The result: (1) Immunization stress had some effects on DMI. All kinds of stresses could have effects on DMI which have significant effects on performance. The decrease of performance resulted in by immunization stress was that due to the decrease of DMI and the new distribution of nutrition. the typical characteristic were fever, lethargy, the decrease of activities and myalgia physiologically. (2) Immunization stress had promotive effect on immune organ (bursa of fabricius, thymus gland and spleen ) as the change on growth. With the growth of chicken, immune organs recovery to normal level, even a little higher than normal level. (3) After vaccination, CD4+T and CD8+T are different, the vaccinated is strongest.