Studies On The Effect Of Selenium Preparation Injected Before Operation On The Stress Status Of Perioperative Sheep

20 sheep were divided into 4 groups.They were Local Anesthesia Controls,Local Anes thesia&Antioxygen,Pantanesthesia Controls and Pantanesthesia&Antioxygen.The Sodium Selenium were injected to the sheep of Pantanesthesia& Antioxygen and Anesthesia& Antioxygen one week before the rumen fistula operatited. The venous blood samples of the sheep were taken at one week before (T0),preanesthesia(T1),1h after incision(T2),6h after operation(T3),12h after operation (T4),1d after operation(T5),2d after operation(T6),3d after operation(T7),5d after operation (T8), 1w after operation(T9), 2w after operation(T10),3w after operation (T11),4w after operation (T12) separately. Thyroid hormones, thyroid stimulating hormone, Selenium, GSH-Px, T-AOC, MDA in blood serum were tested by the corresponding detection methods. The data were analysed by the statistical way.The results showed that the different degrees of variation were occurred on the endocrine system and antioxidant system. The changes of partial Hormone and the antioxidant level were fluctuating with the Content of the Se in organism. The significant changes after operation of COR were showed the stress status of the experimental sheep. The changes of the two antioxidative groups were more mitigate than those of the other groups.And those two were recovered earlier.The changing trend of the four in TH were almost the same, but the TH level of the antioxidant groups were higher than those of the non-antioxidant groups.All of the four groups were showed the symptoms of Euthyroid Sick Syndrome (ESS). The antioxidant capacity of the body was significantly enhanced after the Sodium Selenium injected.The activation of T-AOC and GSH-Px in antioxidant groups was higher than the corresponding Controls. And the changes of the content of MDA in organisms were inverse. It showed that there was a regular inner link between the oxidant defense system and Se concentration. It was found that proper Sodium Selenium injected before operation was effective for strengthenning the antioxidant abilitiy and promoting recovery.