| The paper studies effects of avilamycin and narasin on the non-specific immunity and the ability of immune response of Cyprinus carpio respectively.In order to study the effects of avilamycin and narasin on the non-specific immunity of Cyprinus carpio, avilamycin and narasin were mixed with feed in different concentrations respectively. The concentrations of avilamycin in six groups were respectively 0mg/kg feed (group A0), 2mg/kg feed (group A2), 4mg/kg feed (group A4), 8mg/kg feed (group A8), 16mg/kg feed (group A16), 32mg/kg feed (group A32). The concentrations of narasin in six groups were respectively 0mg/kg feed (group N0), 10mg/kg feed (group N10), 20mg/kg feed (group N20), 40mg/kg feed (group N40), 80mg/kg feed (group N80), 160mg/kg feed (group N160). During the experiment, fishes of different groups were fed with appropriate feed separately, the phagocytic activity of leukocytes, lysozyme activity in serum and the content of serum complement C3 of Cyprinus carpio were tested at 0 day, 7 day, 14 day, 21 day, 28 day, 42 day and 56 day.1. The results indicated that avilamycin has significant effects on the non-specific immunity of Cyprinus carpio. The phagocytic activity of leukocytes and lysozyme activity in serum of group A2 were significantly lower than group A0 on the 56th day; the phagocytic activity of leukocytes, lysozyme activity in serum and the content of serum complement C3 of Cyprinus carpio in group A4, group A8, group A16 and group A32 were all significantly higher than group A0 in 21 days, 14 days, 7 days and 7 days separately, and were all significantly lower than group A0 from the 56th day, 42nd day, 28th day and 21st day separately. Avilamycin with appropriate additive concentrations (4mg/kg feed— 8mg/kg feed) could improve the non-specific immunity of Cyprinus carpio in a short term, but that would restrain in a long term; as the concentrations of avilamycin increased (≥ 16mg/kg feed), the restrain effects on the non-specific immunity would take on rapidly.2. Narasin could affect the non-specific immunity of Cyprinus carpio. The phagocytic index of leukocytes of group N10 was significantly lower than group N0 on the 56th day; the phagocytic index of leukocytes and the content of serum complement C3 of Cyprinus carpio in group N20 were all significantly higher than group N0 on the 7th day, the phagocytic activity of leukocytes, lysozyme activity in serum and the content of serum complement C3 of Cyprinus carpio in group N20 were both significantly higher than group N0 on the 14th day and 21st day; the phagocytic activity of leukocytes, lysozyme activity in serum and the content of serum complement C3 of Cyprinus carpio in group N40 and group N80 were all significantly higher than group N0 until the 21st day, but the non-specific immunity of Cyprinus carpio in group N40 and group N80 were both... |
