A Preliminary Study On The Correspondence Of Longdan Xiegan Decoction In Treating Hepatic Damp - Heat Type

Background:Polycystic ovary syndrome(PCOS) is a kind of endocrine and metabolic abnormalities of department of gynaecology common disease, in recent years, because of its high incidence and on the diagnosis and treatment of complexity, more and more attention. The pathogenesis of PCOS crowd mainly adolescence and childbearing age women, with the development of the society, the change of women’s social status, modern women should bear more from work, study, family, emotional, such as multiple burden, there are quite a number of PCOS patients clinical manifestations in clinical and closely related to liver meridian lesions. Add and subtract gentian purging liver soup on the basis of using the holistic concept and TDS, take more coordinated control system, multi-level, many link, the combination of multiple targets, can obviously regulate liver meridian syndrome PCOS endocrine disorder, regulate the menstrual function for assisted effect is remarkable, and no obvious side effects, the long-term curative effect is better.Objective:The relationship between prescription and syndrome as a research field is a key point in the research of modern Chinese medicine clinical medication rule and the difficulty, To clarify and subtract gentian purging liver soup and liver meridian syndrome PCOS prescription and syndrome corresponding relation, for clinical liver meridian syndrome of diagnosis and treatment of PCOS prescription medication for reference and the basis, In under the guidance of tutor, through exploring and subtract gentian purging liver soup treatment liver meridian syndrome clinical medication regularity of PCOS and observe the liver meridian syndrome clinical syndrome characteristics of PCOS to add and subtract gentian purging liver soup and liver meridian syndrome PCOS prescription and syndrome corresponding relation is preliminary studied.Methods:Research using retrospective analysis method, through more than two years toadd and subtract gentian have diarrhoea liver soup treatment liver meridian syndrome clinical effective cases, 83 cases of PCOS, combined with PCOS clinical investigation scale, the liver meridian syndrome of traditional Chinese medicine(TCM) clinical symptoms of patients with PCOS and gentian purging liver soup used to add and subtract prescription for acquisition, induction, sorting, establish a database entry Epi Data software system, the related information to carry on the liver meridian syndrome PCOS symptoms and induction, the formulas of traditional Chinese medicine and then Epi Data results into SPSS data, using SPSS statistical analysis software, on the basis of study the liver meridian syndrome PCOS clinical Shi Fang law of the preparation of drugs as well as with disease and subtract.Results:1、The study found that 83 cases of liver meridian syndrome in patients with PCOS symptoms of liver by the symptoms of 15 cases of 63 medical records, primarily to add and subtract medicine including hawthorn、Fried Fried malt、rice sprout、angelica root、licorice、rhizoma alismatis、radix geutianae、plantain seed、gardenia、selfheal、radix scutellariae、main astragalus、bupleurum、salvia miltiorrhiza、ricepaperplant pith、radix rehmanniae、zhejiang fritillary、dandelion、forsythia、radix paeoniae rubra、caulis spatholobi、motherwort and so on.2、The study found that 83 cases of liver meridian syndrome in patients with PCOS symptoms of liver by wet and heat and kidney deficiency symptoms of 39 cases of 168 medical records, mainly to add and subtract drugs including radix rehmanniae、hawthorn、fructus ligustri lucidi、radix geutianae、liquorice、alisma、Fried Fried malt、rice sprout、poria cocos、angelica、salvia miltiorrhiza、Chinese wolfberry、red skin、dry lotus grass、dogwood、radix scutellariae、radix ophiopogonis、sichuan dome、yam、plantain seed、gardenia、radix bupleuri、radix paeoniae rubra、rhizoma atractylodis、main astragalus、ricepaperplant pith、safflower、twotooth achyranthes root etc.3、The study found that 83 cases of liver meridian syndrome in patients with PCOS symptoms for liver meridian humid heat and blood stasis symptom of 29 casesof 107 medical records, mainly to add and subtract drugs including radix rehmanniae、hawthorn、angelica sinensis and rhizoma chuanxiong、radix paeoniae rubra、gardenia、ricepaperplant pith、Fried Fried malt、rice sprout、radix scutellariae、radix geutianae、alisma、peach kernel、safflower、zhejiang fritillary、liquorice、achyranthes、main astragalus、selfheal、radix bupleuri、dodder、plantain seed etc.Conclusion:1、The clinical manifestations of liver classics damp and hot type PCOS patients, the clinical treatment of Longdan Xiegan decoction combined with hawthorn、malt、fried guya etc drugs to add and subtract such as promoting digestion and relieving stasis.2、The clinical manifestations of liver classics damp and hot type PCOS and kidney deficiency syndrome of clinical treatment with Longdan Xiegan decoction combined with ligustrum lucidum、poria、cortex moutan、dogwood、yam etc drugs to add and subtract such as invigorate the kidney and essence replenishment.3、The clinical manifestations of damp heat and blood stasis syndrome of liver by PCOS clinical treatment with Longdan Xiegan Decoction with peach kernel、safflower、ligusticum chuanxiong hort hezuo、radix paeoniae rubra etc drugs to add and subtract such as promoting blood circulation to remove blood stasis.