Surgical Diagnosis And Treatment Of Rectal Carcinoid

Objective To investigate the surgical treatment effect for rectal carcinoid patients in Peking Union Medical college hospital.Methods The clinical data of96rectal carcinoid patients between January2003and December2012were collected and analyzed retrospectively.Results Change of bowel habits、abdominal discomfort and diarrhea were primary symptoms. All patients presented no carcinoid syndrome. All patients underwent surgery resection:transanal endoscopic microsurgery (TEM) in38patients, Mason’s operation in4patients, transanal excision in47patients, and radical operation in7patients.84patients received long period follow-up. The5-year survival rate of the patients with muscularis invasion was52.9%, for those without mucularis invasion was81.9%. In a logistic regression analyses, the primary predic factor of prognosis of carcinoid is the deepth of invasion.Conclusion Most rectal carcinoid tumors were without mucularis invasion, and suitable for local resection; but for those invaded into muscularis, radical operation were necessary. Objective To evaluate and compare the long-term and short-term outcome of internal treatment and surgical intervention to ulcerative colitis. Method Over a2year-period from Dec2010to Nov2012, we prospectively collected and retrospectively analyzed the clinical and follow-up data of25patients received surgical treatment for ulcerative colitis, compared with25cases received conventional internal treatment at the same period. The surgical safety, postoperative complications, curative rate, and recurrence rate were compared. Results surgical treatment showed a higher curative rate[88%(22/25) vs.76%(19/25) P<0.05] and a higher incidence of complications[16%(4/25) vs.4%(1/25) P<0.01]. The internal group had a higher recurrence rate [24%vs.12%]. Quality of life were termed as Karnofsky marks in both groups. Conclusion Surgical treatment for ulcerative colitis is more curative than internal treatment, while holding a higher incidence of complications. Conventional internal treatment offers good control of disease and improves quality of life, while the incidence of recurrence is higher than surgical treatment group. For those patients suffer repeat recurrence after internal treatment, surgical intervention may be necessary.