The Manufacture Of 15% Bensulfuron-methyl·Mefenacet Effervescent Tablet And Biological Tests

Nowadays the development of the pesticides formulation is high effect, safety, low toxicity and convenience in use. As a new formulation of pesticides the effervescence has unique advantage.it is a embranchment of JUMBO. According to the development of the pesticides formulation. The effervescence is initiated by Japanese. It is used in medicament widely. The effervescence had used in pesticide for not long time. It has unique advantage in paddy, which can reduce the work force and it has few effect on environment. Therefore excogitate a paddy field one-off herbicide is very important. This article selected a high effect herbicide bensulfuron-methyl which counteract gramineous weed and mefenacet which counteract latifoliate weed. And make these two medicament to a paddy field one-off effervescence herbicide.This article think over the Suspensibility, time of disperse, and rigidity. Choose and determine the carrier, wetting agent, dispersant, adhesive. At last the prescription is bensulfuron-methyl 1%, mefenacet 14%, lignin sulfonic sodium 2%, twelve alkyl phenyl sulfonic sodium 2%, citric acid 20%, sodium bicarbonate 20%, arabin 6%, anhydrous sodium sulfate35%. Volume of inject. 10μlEstablished a HPLC method about 15% bensulfuron-methyl-mefenacet. The condition is that flow : methanol: water: acetic acid=71.5:28:0.5, wavelength is 256 nm, temperature is 30℃, velocity of flow is 1 ml/min, the proportion of callback about bensulfuron-methyl and mefenacet is 99.6～99.69% and 98.97～99.42% , coefficient of variance is 1.86 %and 1.66%. It is accord with the need of normal quantity analyse. Put the effervescence table into the condition that 54℃ continuance 14 days. After that analyze the component of the effervescence , both the bensulfuron-methyl and mefenacet 's decompound are all less than 5%.We do toxicity experimentation. The 50% mefenacet WP and 30% bensulfuron-methyl WP are contrast. Maize, wheat and cuke are the plant that were treated by these herbicides. The result is that the LC50 about the root length of 15% bensulfuron-methyl-mefenacet is better than the 50% mefenacet WP and 30% bensulfuron-methyl WP.This prescription accord with the standard of pesticide and the effect is better than other kinds of herbicide. It have the value of popularize in business .