Study Of Chinese Traditional Medicine SF Antihypertensi On Pharmalodunamics And Antihupertensi On Mechani

This experiments according to the side effect of current anti- high blood pressure medicine is big, and badly respond many, then develop the new Chinese herbal medicine product for purpose, to Chinese herbal medicine SF anti- high blood pressure function and decline to press the mechanism to proceed research, with the period completely developping of medicine for rightly herein clinical fulfillment and later on provide the theories with experiment data.With the narrow method of left kidney artery two-kindey-on clip renal big rad hypertension model. The rat was given different does SF ig, Result Chinese Traditional Medicine SF can obviously decrease 2KIC rat blood pressure , but have no to measure the dependence; can obviously decrease the each weight of myocardial the parameter, the left room calcium leave the son, protein, MDA, aorta the calcium leave the son to contain-to measure, strengthenSOD, NO the activity, elucidation the Chinese herbal medicine SF to can converse the left room fleshy, its function and anti- free radicals is with the calcium compete anti- the function is relevant.From bestow the drug pass the cat' s acanthi artery can know the blood pressure no change; In the interdiction ganglion experimentation, and behind stimulate to the medicine before stanza, after the stanza fiber, haw shrink extent have no obviously difference with to before msdicine to the medicine to the medicine. In the α-receptor antagonize experimentation, P -receptor antagonize experimentation, tip drug when former and after NE, ISO rise the extent of the blood pressure have no difference; Wet to experiment the inside in the benefit, and give in the reagent 2h, 3h, 5h, 6h empress, beat the rat the row urine to measure to compare with matched control to have no difference, and rent with masculine gender to compare the difference, Above and consequently express the Chinese herbal medicine SF the rat the outside week to decline to press the mechanism, but impassivity stanza the break the function a -receptor antagonize, α -receptor antagonize function, β -receptor antagonize functionand the benefit function, its function with the calcium fleshy anti- the function is relevant.Get across the method of the decoction, mellow to lift the method, use water to distill and hot reflux method the filter the good for the method of the distill. Results Chinese Traditional Medicine SF Chinese herbal Medicine SF the validity withdraw the way to decoction the method, mellow to life the method and hot reflux method.