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Antigenin, Dynamic Of Lhrh Antibody And Security Of Genetic Engenieering Lhrh Vaccine

Posted on:2002-02-12Degree:MasterType:Thesis
Country:ChinaCandidate:G M GongFull Text:PDF
GTID:2133360032456443Subject:Prevention of Veterinary Medicine
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There is little cross梤eaction between aLHRH and mLFIRH by indirect inhabitory ELJSA .There is little reaction between L2 and standard mLHRH antibody, butthe L2vaccine as the immunocastration effects.Study on the dynamic change of LHRH antibody by mouse and pigs indicates that the antibody which gets highest downloads quickly after the first and second immunizedThere states of LHRH vaccine used in rabbits and mouses which indicates that the immunogenecity of Stapylococcus Aurous Cowan I optimization rebuilded group is stronger than the immunogenetical combinants group , the two groups are better than the group I.In the detetion of LHRH residuls , there was no LHRH antigen in the blood and muscles two day later, no LHRH antigen in liver four days later, in the spleen on the tenth day , LHRH antigen dissappeared completely. Mixed the meat of vaccined rabbit to the feedstuff to feed the mouse for 35 days and it indicates that there is no any potential threat to the generative health of human even having the meat of vaccined animalsThe detection of LI-IRH antibody by vein and oral with LFIRH serum indicates that it will not affect the generative health of human for its effect of neutralizing LHRI-1 hormone after absorbing active LHRH antibody because of having the meat of vaccined animals. Analyzing the quality of meat of three groups, it indicated there was no apparent difference in the nutrition components between the experimental and the control group. The difference of cobblers atrophic between the first immunized and the second is little.Sequence of Li and L2 are sent to the EMBL(by BLAST2 search service)and no existing protein is high homology with the present LFIRH protein .The analyzation of the exposure percengtage , that is hydrophilicity and hydrophobe of the LHRH indicates thatantigenecity of mLHRH peptide in the different fusion protein and the same amino梐cid in the different fusion protein is different.
Keywords/Search Tags:Engenieering
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