Preparation Of Supported Au (â… ) Catalysts And Its Application In Conia-Ene Reaction And FDU-NHC/Pd (â…¡) Catalyzed Coupling Reaction

The research of novel and efficient catalytic materials for heterogeneous acids and bases, metals and asymmetric catalytic process become one of the major investigations in the field of catalytic materials design and application.This thesis was focused on two sections. In the first section, a series of supported Au (â… ) catalysts were synthesized, characterized and applicated in Conia-Ene reaction. Gold catalysts, because of their unique properties, have now become a well-established best choice for many chemical transformations with pre-eminence established now in both heterogeneous and homogeneous processes. Gold-catalyzed reactions often proceed under mild conditions and obtain high yields in extremely small amounts so that they play an important role in organic synthetic chemistry. Phosphine ligands with Au (â… ) catalyzed Conia-Ene addition reactions are one of the representatives. However, these traditional homogeneous catalysis processes often suffer several drawbacks, such as difficulties in recovering and recycling, an easy contamination of metal species in the reaction products, etc. The purposes to overcome these drawbacks have led to the immobilization of homogeneous Au catalysts. The supported catalysts light the pollution of environment and promote the development of green chemistry for the mild reaction conditions, good activity, low consumption of precious metals, especially the advantage of recycling. In this thesis, different types of materials (SBA-15, FDU, PEG-OMe) have been functionalized by phosphine ligands, and then mix with homogeneous Au (â… ) catalysts, thus obtain several different supported Au (â… ) catalysts. Their catalytic abilities were studied via Conia-Ene Reaction. The results indicated that the catalyst for the synthesis of DPC PEG/Au (â… ) catalyst has high activity and recyclability. Further studies on the different substrates are in progress.In the second section, we reported FDU-15-supported N-heterocyclic carbene-palladium catalyst (FDU-NHC/Pd (â…¡)) for Sonogashira coupling reaction and homocoupling of arylboronic acids. FDU-NHC/Pd (â…¡) was highly active for Sonogashira reactions of aryl halides and terminal alkynes. Both electron withdrawing and electron donor substrates could obtain the corresponding product with a satisfying yield (45-98%) and the catalyst could be reused 10 times. The catalyst also shows excellent activity in homocoupling of arylboronic acids, the choice of optimum conditions of work is in progress. In addition, FDU-NHC/Pd (â…¡) was characterized by XPS, XRD, N2 adsorption-desorption, and TEM, etc. Those results indicated that the catalyst well preserved the mesostructure after fictionalization.