Studies On The Photochemistry Of Quinolone Derivative In The Different Resteicted Medium

Recently, supramolecular photochemistry has attracted much attentions of scientists as a new subject. Supramolecular photochemistry is the process of which supramolecule is molecular recognition, catalysis and information transfer by photochemical catalysis. The photochemistry in the resteicted medium that is one of the host-guest supramolecule has become the focus of study. The photochemistry of guest molecule in the special environment or organized structure has highly selectivity and specificity. The resteicted medium can control the direction of reaction by the special aperture, environment or by special acting force. It can make the guest molecule have orientation and highly selectivity.The paper mainly studies the photochemistry of quinolone derivative in the different resteicted medium. We discuss the the photochemistry of quinolone derivative in the cyclodextrin and the mixture system of cyclodextrin and chiral inducer, and compare the difference of stereoselectivity. The structures of some compound and the four chiral inducers have been definited by IR, 1H NMR, 13C NMR, HPLC and so on.In this dissertation, the reaserach work can be divided into three parts:First, we discourse the development of the organic photochemistry and introduce the supramolecular photochemistry, and propose that the host-guest supramolecule is the emphasis of the research. The photochemistry in the resteicted medium has become the hot spot of the research as the highly selectivity and specifity.Second, we synthesize the compound and represent them. We synthesize two different photochemical substrates and a series of long chain chiral compound, S-a, R-a, R-b, and R-c. And we have defined the structures of them.Third, we discuss the photochemistry of quinolone derivative in four different environment: no inducer, chiral inducer, cyclodextrin and the mixture system of cyclodextrin and chiral inducer. We compare the difference of the stereoselectivity in cyclodextrin and the mixture system of cyclodextrin and chiral inducer. It is found that in the reasonable condition the mixture system of cyclodextrin and R-a can raise the selectivity of 3a, and the mixture system of cyclodextrin and R-c can advance the stereoselectivity of 4a and 4b. This resteicted medium has better effection than the only cyclodextrin.