Synthesis And Properties Of Several Water-soluble Perylene Derivatives

Perylene derivatives are characterized by a strong absorption in visible region of spectrum and exhibit a similarly strong fluorescence. Most perylene derivatives dyes display emission above 500 nm that benefits by the improvement of the signal/noise ratio in biological system owing to the presence of high autofluorescence of living cells. A lot of effort has been made to solve their water-solubility. With high fluorescence quantum yields (FQYs) and photostability, their potential as fluorescent dyes constitute fertile soil for research on fluorescent labelling.Chapter 1: The research and applications of perylene derivatives have been reviewed, especially for the water soluble perylene derivatives.Chapter 2: A series of water-soluble and high fluorescent perylene derivatives have been synthesized by indroducing pyridine oxide moieties to perylene core or to imide groups. The UV-vis and emission spectra of the derivatives in different ratio of THF and H₂O were discussed. One novel colorimetric and fluorometric probe based on perylene bisimide derivative (8) has been developed for Zn²⁺ detection with high selectivity and sensitivity.Chapter 3: A series of water-soluble and high fluorescent perylene derivatives have been synthesized by indroducing N-oxide pyrrole groups. The electrostatic potential maps (MEP) were calculated from B3LYP/6-31G* density functional calculations. And the photophysical properties were also researched both in organic solvent and water.