The Study On Preparation And Properties Of Ploy Methyl Methacylate-based Artificial Bone Plates Composite Materials

Bone tissue damage caused by various diseases, injury and accidents, has become a common and frequently occurring disease. In clinic, a number of different classes of materials, including biomedical metallic and alloy materials, biological ceramics, and biomedical polymer material, have been used to replace the damaged bone. A variety of materials and products has been applied according to the requirements of different positions.In this paper, Polymethyl Methacrylate based (PMMA) composite material was selected for the study of skull and fracture fixation plates. Inorganic fiber-reinforced bone plate of PMMA/HA composite material was synthesized. The Structural characteristic of the as-synthesized material is hydroxyapatite powders coated on the inorganic fibers and PMMA composite surface, which improved the mechanical properties of composite materials while coMPared with the single PMMA. A comprehensive performance is better than the human skull, tibial. Moreover, the bioactivity and biocoMPatibility were also improved by this method.Multi-layer coating and mould pressing technology were used to prepare composite material bone plate. The several factors, such as the percentage of resin, molding temperature, molding pressure and molding time, which affect the composite performance, were studied to investigate the physical and mechanical properties of composite materials for artificial bone plate. Mainly works focused on the relationship between the percentage of resin and the toughness of the composite material. Scanning Electron Microscopy was used to investigate the microstructure of composite materials. National standards were used for the determination of the percentage of resin, density water absorption, and mechanical strength. The Wettability of the composite material was tested by water droplets. According to the experimental results, the optimal composition and process parameters were gained:The molding temperature is 120℃, the molding time is 8h,the molding presure is 14MPa.When the percentage of resin is 55.58%, the materials have the best mechanical properties,the mechanical test results are: tensile strength at 80.5MPa, compresive strength at 129.9MPa, flexural strength at 100.7MPa, shear strength at 156.3MPa, iMPact resistance at 13.6KJ/m~2 ,which are better than mechanical strength of human skull,equal to the mechanical strength of human tibia.The highest density is 1.36 kg/m~3, and the water absorption less than 0.9%.To enhance the bioactivity and osteogenesis further, surface modification of composite materials and the stability test were performed in simulated body fluids (SBF). The results showed that: bone-like apatite layer were deposited on the surface of the composite materials after immersed by SBF. Needle-like, flake and near-spherical bone-like apatite, which belongs to B-type carbonated hydroxyapatite with good combination of human tissue, were formed on the surface of the samples. Mechanical strength (tensile strength, compressive strength) test results showed that the mechanical properties of materials could maintain the basic stability, which makes the composite materials more safety and reliability.