New Method To Improve The Analysis Sensitivity Of Gas Chromatography By Rapid Pressurization On Column

With the development of the science and the demand of sensitive analytical method, the analysis sensitivity (AS: the quotient of peak high by peak area) improvements in gas chromatography, which is a good and common tool in trace analysis, is increasingly interested.In this work, a new method to improve the analysis sensitivity of gas chromatography by rapid pressurization on column was found. The new method of rapid pressurization on column, which consisted of two parts: the rapid pressurization on the top and the end of column, was adapt to the gas chromatography-flame ionization detector system. An improvement of 6 to 45 times in analysis sensitivity was obtained with limit hardware modification on the GC-FID system. The rapidness and convenience in pursuing the best operating preferences made the method widely available in both common and trace analysis.It was proved in the experiments that a 6 to 10 times improvements in AS was made by rapid pressurization on the top of column, while 8 to 45 times increased by the end-of-column mode. The detectability was also improved with a limit quantity of 10-13 mols by the ordinary direct injection with a small sampling amount. In addition, the method of the rapid pressurization on column retained the necessary resolution of the analyzing process, and effectively meliorated the peak shape as well.In a word, the method of rapid pressurization on column was proved to be a new estimable way of improving the analysis sensitivity of GC-FID system, and was able to be generalized in the future work.