| Preparative gas chromatography is one of the efficient methods to separate azeotrope. For it has the advantages of low energy consumption and good separation result, preparative gas chromatography has a wide range of application in separating a large amount of azeotrope in chemical and pharmaceutical industry.Now preparative gas chromatography has some difficulty in applying on a large scale in the industry. There are two reasons mostly. First, the chromatogram column with large diameter is needed in the industry, but the regular carrier of gas chromatography can't be applied on a large scale. Second, there needs large-scale injection in the industry, however, it hasn't been realized until now.Based on the two problems of preparative gas chromatography, this paper proposed a new method using wire mesh packing as carrier of the stationary phase. The chromatogram column was configurated usingθring stainless steel packing as the carrier and cetomacrogol 20000 as the stationary phase. A new injection mode which is called the injection mode of gasification in advance was proposed. The feed was gasified before the injection in this mode.The separation process of gas-liquid chromatography using wire mesh packing as carrier of the stationary phase and adopting the mode of gasification in advance as a new injection method was studied. The experiments using binary azeotrope of 1-propanol and water as the feed were carried out. This paper investigated influence of some operating parameters such as injection amount,column temperature,flowrate of carrier gas,column diameter and packing size on the separation of azeotrope of 1-propanol and water. The results showed that it was totally feasible to use wire mesh packing as carrier of the stationary phase of gas-liquid chromatography. The injection mode of gasification in advance was easy to control and appropriate to scale-up in the industry. In addition, the designed chromatogram apparatus can separate azeotrope normally.
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