Study On The Preparation And Quality Standards Of Qiancaoxiaoshi Granule

Compound Qiancaoxiaoshi granule consists of Lysima chiachristinae Hance , Herba Pyrrosiae Linguae , Spora Lygodii, Dianthus superbus Linn and so on. It has functions of clearing and dispersing damp heat, eliminating stone, micturating and relieving pain, softening hardness and dissipating stagnation. It is always used in curing urinary systerm stone.Qiancaoxiaoshi granule was originated from an effective prescription in clinical practice of many years. We researched systemically preparation and quality standard. Using orthogonal design to optimize the extraction technology and techniques of preparation of Qiancaoxiaoshi granule, selected the best preparation process;The study of the quality control standard takes the methods of microscopical identification, chemical identification, TLC, HPLC and establish its quality standard, so we can make sure the quality of Qiancaoxiaoshi granule is controllable.In addition, primary stability was tested in three lots of pilot study samples during the period of three months, wechecked the particle size, water,dissolving, difference in packing volume, quality standard and mierobiallimit for disintegratio, the results were according with order.According to the researeh, the results showe that the every index mark were normal in the experiment period, and lay down a solid basis in drug design and development.