Study On The Functional Composite Pollen Sofe Capsule

Bee-pollen is a kind of valuable natural nutrient resources which deserved to studied and explore,it is rich in nutrient components that needed by human boby,and contains kinds of functional ingredients which are absolutely necessary to our hearlth because of its special function.It was effective in treating Prostatic Diseases with improved the efficacy and without reverse effect,suitable for long-term consumption. In this paper,The rape bee pollen which is effective in treating Prostatic Diseases was used as raw materials made its soft capsules.The curative effect extracting procedure of nutrition in rape bee pollen.The formula of Bee Pollen Soft Capsule complex emulsion stabilizers were studied,and the quality standards of Functional Composite pollen soft capsule was summarized.1.At the 50℃(±1℃)condition,rape bee-polllen is extracted by mixed solvent (volume ratio of 5%ethanol to 10%acetio acid is 30:1)frist time and extracted by 85%ethanol second time.The test results is referenced to the effect of the rape bee pollen extract on Hyperplasia of Prostate induced testosterone propionate in mouse, the extracting conditions of the rape bee pollen are as follows:first material ratio is 1:6,first extracting time is 2.5 hours,second material ratio is 1:4,second extracting time is 3 hours.2.Through uniform-design,the recipe of rape bee pollen capsules complex emulsion stabilizers was optimized through uniform-design.Test results are used multiple stepwise regression analysis to made the multiple regression equation by the SAS statistical software:Y=-298.64-4.86X₁X₂+41.60 X₂X₄+93.10X₂X₅+423.92X₄X₆-137.32 X₅X₆.The optimal formula is X₁:6.5 g,X₂:5.5 g,X₄:0.35 g,X₅:1.10 g,X₆:0.35 g.3.Developed the quality standards of functional composite rape pollen soft capsule,and the analysis indexes of product are in accordance with the set of GB16740-1997 entirely.The contents of total flavones and 10-HAD are 9.31 mg/100 g and 390 mg/100 g.The standards provide the theoretical basis for the industrial production of functional composite rape pollen soft capsule.