Study On The Removal Of Byproduct Nitrogen Dioxide From The Mixture Of Inhaled Nitric Oxide Produced By Pulsed Arc Discharge

Nitric oxide was identified as an endothelium-derived relaxing factor (EDRF) at 1987, which can relax the blood vessel selectively, reduce the pressure of artery of lung. Inhaling NO at low concentration (3-20ppm) can be used to cure acute respiratory distress syndrome (ARDS), high blood pressure and some illnesses related to lung. The medical NO at present is deposited in a cylinder at high concentration (500-800ppm), which is discommodious and easy to leak out when diluting. The present study produce nitric oxide by pulsed arc discharge, which can meet the clinical standard of NO2<3ppm,NO2/NO<5% by a purifying process, and an apparatus for curing acute respiratory distress syndrome was designed, as well as some applications to animals were finished.Some kinds of sorbent, including the charcoal, the bamboo-charcoal, the columnar activate carbon, the particle active carbon, the natrium-soda lime, the 3A molecule sieve, the 4A molecule sieve, the 5A molecule sieve, the 13X molecule sieve and so on were studied to absorb NO2 selectively. The result shows that the bamboo-charcoal, the charcoal and Columnar Activated Carbon could absorb NO2 greatly, which could purify NO produced by discharge to meet the requirement for clinical application. The BET and BJH test of the bamboo-charcoal, the charcoal, the columnar activate carbon showed that the columnar activate carbon had the largest surface area, most of pores were micropore and mesopore; the charcoal was only a half of surface area compared with the columnar activate carbon, most of pores were micropore and macropore; the bamboo-charcoal had the least surface area, most of pores were micropore.Several sorbent were dipped in sodium hydroxide and ammonia to change their surface groups for a better selectivity of adsorption of NO2.A catalytic reactor was designed, and the activity, the selectivity, and the lifetime of molybdenum to reduce NO2 were studied. Reducing NO2 by charcoal and active carbon was carried out, and Cu+ or Cu0 was loaded by dipping; their activities to reduce NO2 were studied. With the apparatus of curing acute respiratory distress syndrome, 40 cases of animals were applied to inhale NO in the branch of pulmonary in Xiehe hospital, Huazhong University of Science and Technology.The result shows that inhaling NO and O2 indeed could improve the status of animals, which pave the way for the application to people.The flow distribution of some different structures of discharge reactor were simulated with the software of fluent 6.1, an optimized structure of discharge reactor was designed.