The Synthesis And Identification Of Organic Active Molecules

Halohydrocarbon is one of the most important organic compounds and widely used in chemical industry, agriculture, material, environmental protection and modern organic synthesis. High chemical characteristic together with various biological activities make them have crucial in the studies of basic theory, modern synthetic application and synthetic methodology.In this paper halohydrocarbon was studied as following: first, the important role and application of halohydrocarbon were introduced. The synthesis methods of halohydrocarbon were reviewed for the research and application. In these methods, the halogenation of compounds containing hydroxyl group was particularly summarized. Besides these methods of introducing different halogen atom to aliphatic hydrocarbon and aromatic hydrocarbon were also reviewed.Second, several organic compounds containing halogen atom were designed and the synthesis methods of related molecular were researched. The target molecular were classified according to their structure properties and used into the synthesis of natural product, such as diterpenoids , neolignans and organic ligands .In addition they were widely applied in Heck reaction, Suzuki reaction, Stiller coupling.Third, the related halohydrocarbon was obtained from benzyl alcohol and aliphatic alcohol. In the aromatic compounds containing hydroxyl group, the halogenation, functional protection, reduction, oxidation and eaterazation were studied. The halo atom was directly introduced, and developing the research. The fine hylogenation reagent was chosen through contrast experimental conditions, yield and friendly.This paper reported the synthesis methods of target molecules and intermediates. The structures were determined by IR and 1HNMR.