Research Of Nanometerfication & Stabilization Effect Of Degraded Algal Polysaccharide For Nanoselenium In Aqueous Solution

Selenium in the nanometer scale has nice bio-availability and bio-activity, but low-toxicity. It is a great medicine for supplement of selenium. Nanoselenium(nanoSe⁰) is difficult in existence in aqueous solution without protection. So how to preserve nano-Se⁰ by surface-modified has the significance to make nanoSe⁰ medicine. Algal polysaccharides have good anti-virus and anti-cancer activities. We have investigated algal polysaccharides in the use of nanometerfication and stabilization effect for surface-modifying nanoSe⁰ in aqueous solution. We managed to combine algal polysaccharides and nanoSe⁰, and tried to co-operate them with union of bio-activity.1. Research of spectroscopy of algal polysaccharides and degraded algal polysaccharides.Algal polysaccharides are the macromolecular carbohydrate of alga. They have characters of water-solubility and concreting, anti-virus and anti-cancer activity. Due to the large molecular weight and low water-solubility, their clinical usage is narrow. We prepared the algal polysaccharides by oxidative degradation with H₂O₂ under the ultrasonic wave. The degraded algal polysaccharides had good content of sulfated group and low 3,6-anhydro-galactose. They can be taken in more easily. So it enhanced their bio-activity. Algal polysaccharides and degraded algal polysaccharides were characterized via Resonance Rayleigh Scattering (RRS), UV-Vis and laser light scattering image. In terms of the results, we can provide the bases to further study the nanometerfication and stabilization effect of degraded algal polysaccharides for nanoSe⁰ in aqueous solution.2. Nanometerfication & stabilization effect of degraded undaria pinnatifida charv. suringer polysaccharide for nanoselenium in aqueous solution.In the presence of degraded undaria pinnatifida charv. suringer polysaccharide (DUP), appropriately excessive L-Ascorbic acid(Vc) and selenium dioxide(SeO₂) reacted to prepare nanoSe⁰ in aqueous solution at room temperature. It was characterized via Resonance Rayleigh Scattering(RRS), laser light scattering image...