Preparation Of Fluorescent Microspheres By Dispersion Polymerization And Characterization

Fluorescent microsphere is a new kind of functional polymer material which is mainly in biomedical engineering area. Studies on the preparation of the fluorescent microsphere are of great practical significance because this kind of material used in China is imported. In this paper, dansylallylamine monomer was synthesized and four kinds of fluorescent microspheres were prepared with dansylallylamine or Alq3 as monomer by copolymerization and physical methods.The structure of the monomer and size and size distribution were characterized.New monodisperse fluorescent microspheres with the size about 500 nm and PDI 0.2 were prepared by dispersion polymerization of dansylallylamine with styrene in methanol/water reaction media using polyvinylpyrrolidone (PVP) as a steric stabilizer and 2,2'-azobisizobutyronitrile (AIBN) as an initiator in suitable condition for imploiting the method of copolymer fluorescent microspheres. The microspheres emit at 515 nm.New monodisperse fluorescent microspheres with the size about 1.619μm and PDI 0.4 were prepared by dispersion polymerization of dansylallylamine with methyl methacrylate in methanol/water reaction media using polyvinylpyrrolidone (PVP) as a steric stabilizer and 2,2'-azobisizobutyronitrile (AIBN) as an initiator in suitable condition for imploiting the method of copolymer fluorescent microspheres. The microspheres emit at 520 nm.Seed particles with the size about 500 nm and PDI 0.2 was prepared and then were further swollen to about four times in diameter by means of dymanic swelling method.Fluorescent microspheres by physical encapsulating method of methyl methacrylate and Alq3 with the size about 3-5μm and PDI 0.2 were prepared.