| This thesis is focused on the electrochemical analysis of some pharmaceutical, such as Chinese herbs and pesticides. The electrochemical behavior of Aristolochic Acid was investigated at glassy carbon electrode. Multi-wall carbon nanotubes / Dihexadecylphate (MWCNT/DHP) modified electrode was prepared and characterized, furthermore, it was successfully applied in the determination of benzimidazole fungicides including carbendazim (MBC) and thiabendazole (TBZ).In the first part, the importance and analytical methods for pharmaceutical was summarized. The application of electrochemical analysis methods and carbon nanotubes materials in electrochemical analysis was emphasized.In the partⅡ, some electrochemical techniques such as Cyclic Voltammetry (CV), Linear Sweep Voltammetry (LSV), Chronocoulometry (CC) and Differential Pulse Voltammetry (DPV) were used to study the electrochemical behavior of Aristolochic Acid (AA) at glassy carbon electrode (GCE). In the B-R buffer solution of pH 5.0, a rapid and sensitive electrochemical analysis method was developed for determination of AA. The peak current is proportional to the concentration of AA in the range of 8.0×10-7～6.0×10-6molL-1 with a detection limit of 1.6×10-8molL-1. This method was successfully applied in analysis of AA in Aristolochiae Manshuriensis (Chinese Herb) with the recoveries of 85.693.3%, and the RSD of 2.13.5%(n=5).In the partⅢ, the multi-wall carbon nanotubes/Dihexadecylphate (MWCNT/DHP) modified electrode was prepared and characterized by field emission scan electron microscope (FESEM), Cyclic Voltammetry (CV) and AC impedance techniques. In the B-R buffer solution of pH 4.5, by using DPV method, a very sensitive electrochemical analysis method was developed for determination of carbendazim (MBC) at MWCNT/DHP modified electrode with the detection limit of 6.9×10-9molL-1.Combined with the solid phase extraction(SPE) technique, this method was applied to detect MBC in the environmental water sample. The recovery was in the range of 83.1～90.2%,and the RSD of 1.5～3.2%(n=3).In the partⅣ, the multi-wall carbon nanotubes/Dihexadecylphate (MWCNT/DHP)... |
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