| Recently, with the development of TCM preparations, the application of dispersible tablets has been paid more and more attention and become a promising TCM preparations. Compared with traditional dosage forms, dispersible tablets features larger superficial area faster soluble speed, accurater dosage, easier absorption and more convenient for being taken. By corydalis rhizome dispersible piece after clinical confirmation the drug efficacy is high. This experiment develops corydalis rhizome dispersible tablets is by corydalis rhizome, designed by Chinese Herb Medicine new medicine technology, by scientific method extraction and purification, it becomes modern Chinese Herb medicine new preparation.We have established the best extract condition, process by orthogonal experiment design. The active principles were gathered and purified through Macroporous adsorbing resins. Through joined the appropriate supplementary material to optimize the disperser piece formation craft, the rate of finished products results in to be high and conformed to People's Republic of China Pharmacopoeia. Simultaneously the qualitative study is conducted by the thin layer chromatography. we have adopted the UV and HPLC methods to carry out the quantity analysis of the dispersible tablets, acquiring the result by measuring the content of mass alkaloid and macleyine we can set up Preparation technique of dispersible tablets effectively.Thereby, this experiment provides scientific basis for production, the standardization of herbs and preparations were established. |
